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Widmer RJ, Collins NM, Collins CS, et al. Digital health interventions for the prevention of cardiovascular disease: a systematic review and meta-analysis. Mayo Clin Proc. 2015;90:469-80.
Do digital health interventions, using technology such as the Internet or telephone, help reduce cardiovascular disease outcomes or risk factors for cardiovascular disease?
Cardiovascular disease is common, and risk factors include being overweight, smoking, diabetes, high cholesterol, and high blood pressure. Digital health interventions include telemedicine, Web-based (Internet) strategies, e-mail, mobile phones, mobile applications, text messaging, and monitoring sensors. These methods have been used to help people monitor their health and change behaviors, reducing their risk for preventable diseases.
The researchers did a systematic review, including studies up to January 2014. They found 51 studies with 24,054 people. The average age was 54 years, and 54% of participants were men. 9 studies were randomized controlled trials.
Any digital health intervention was compared with usual care in adults wanting to prevent cardiovascular disease.
Outcomes were cardiovascular disease outcomes (cardiovascular events, hospitalizations, or all-cause mortality) and lowering risk factors for cardiovascular disease (e.g., weight, body mass index [BMI], blood pressure) and 10-year risk scores for cardiovascular disease (Framingham Risk Score).
39 studies focused on preventing cardiovascular disease in people without cardiovascular disease, and 13 focused on preventing future events in people with cardiovascular disease.
Most studies were 6 to 12 months in duration.
The quality of the randomized controlled trials was good.
Based on the randomized controlled trials, digital health interventions reduced cardiovascular outcomes by about 81 events out of 1000.
Based on randomized controlled trials and observational studies, digital health interventions:
Digital health interventions reduce cardiovascular disease outcomes and improve some risk factors for cardiovascular disease.
Number of studies (number of people)
Digital health intervention
Absolute effect of digital health intervention
Cardiovascular disease outcomes*
About 81 fewer events out of 1000