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When sadness won't go away: What to know and what you can do
Jan 6, 2026 - McMaster University -
The Bottom Line
⏱ 2 min read, 2 min video
Everyone has days when they feel down. But if those feelings linger for years, it might be something more. Persistent depressive disorder (PDD) — formerly called dysthymia — is a chronic form of depression that often goes unnoticed, especially among older adults who may think it’s simply part of aging or their personality. In this short video, clinical psychologist Dr. Danielle Rice discusses what persistent depressive disorder is, why it’s easy to miss, and how treatment can help.
Persistent depressive disorder is a mental health condition where low mood lasts for at least two years and symptoms are never absent for more than two months at a time. While symptoms may be less intense than they are with major depression, they are chronic and can make everyday life difficult. People with persistent depressive disorder often:
Feel sad or hopeless most days
Struggle with low energy and poor sleep
Have trouble concentrating or making decisions
Lose interest in activities they once enjoyed
These feelings can make even simple tasks feel overwhelming.
Special considerations for older adults
Symptom differences: Symptoms may appear as physical complaints (aches, fatigue, appetite changes), memory problems, or withdrawal from social activities rather than obvious sadness.
Late-life onset: PDD can develop for the first time in older age, sometimes with fewer early psychiatric symptoms, but with a significant impact on daily functioning.
Grief vs. PDD: Bereavement is common in later life, so healthcare providers must distinguish normal grief from PDD.
Comorbidity: PDD often coexists with chronic health conditions or other mental disorders, though some older adults may experience a “pure” form without other psychiatric diagnoses.
Underdiagnosis: Depression in late life is frequently missed because symptoms are mistaken for aging or physical illness, or there is reluctance to seek help.
Why its easy to miss
Because symptoms are long-lasting and may be less intense, many people assume this is “just how life is.” Unfortunately, untreated persistent depressive disorder can worsen over time and lead to more severe depression. Recognizing the signs is the first step toward feeling better.
What can help?
The good news: persistent depressive disorder is treatable. Evidence-based options include:
Lifestyle strategies like regular exercise and connecting with supportive communities or groups.
Cognitive behavioural therapy (CBT) to change negative thought patterns.
Antidepressant medications prescribed by a doctor.
Dr. Anthony J. Levinson is a Professor at McMaster University and holds the John R. Evans Chair in Health Sciences Educational Research and Instructional Development. One of the co-leaders of the McMaster Optimal Aging Portal, Dr. Levinson is also a psychiatrist with a special interest in medical psychiatry, neuropsychiatry, and preventive psychiatry. His area of research interest includes online learning to improve healthcare provider and patient education.
Author Details
Danielle Rice
Dr. Danielle Rice is an Assistant Professor at McMaster University in the Department of Psychiatry and Behavioural Neurosciences and a clinical and health psychologist and clinical lead at the Mood Disorders Treatment and Research Clinic at St. Joseph’s Healthcare in Hamilton, Ontario.
References
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Bhalla RK, Terpstra AR, Butters MA. Late-life depression. In: Parsons MW, Braun MM, eds. Clinical Neuropsychology: A Pocket Handbook for Assessment. 4th ed. Washington, DC: American Psychological Association; 2024:640-667. D oi:10.1037/0000383-024
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Canadian Coalition for Seniors' Mental Health. Canadian Guidelines on Prevention, Assessment and Treatment of Depression Among Older Adults. Toronto, ON: Canadian Coalition for Seniors' Mental Health & Mental Health Commission of Canada; 2021.
Lam RW, Kennedy SH, Adams C, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults. Can J Psychiatry. 2024;69(5):403-418. doi:10.1177/07067437241245384
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DISCLAIMER: These summaries are provided for informational purposes only. They are not a substitute for advice from your own health care professional. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the McMaster Optimal Aging Portal (info@mcmasteroptimalaging.org).